Voltron voltage sensors

Voltron is a genetically encoded voltage indicator (GEVI) that utilizes photostable synthetic dyes rather than fluorescent proteins to report neuronal activity. Use of synthetic dyes can extend imaging time over tenfold relative to GEVIs that use fluorescent proteins.

 schematic of Voltron construct and how it works

For details and methods, see Abdelfattah et al., 2018.

We have Voltron transgenes under the control of UAS or lexAop.