MicroRNA gene mutations

The following table shows knockout mutations in microRNA (mir) genes. Most were generated by Steve Cohen and colleagues by homologous replacement of mir gene sequences by miniwhite-, GAL4- or GFP-expressing transgenic insertions. In some cases, clusters of mir genes were deleted rather than individual mir genes.

The mutations donated by Steve Cohen are described Chen et al. (2015), Systematic study of Drosophila microRNA functions using a collection of targeted knockout mutations. Dev Cell 31:784.


Related links   UAS-mir sponge   RNAi   UAS-mir