UAS constructs for non-Drosophila odorant receptors

Non-Drosophila odorant receptors expressed under UAS control can be found here.

The Aedes and Anopheles constructs are maintained with the aberrations Df(2L)dp-79b and Dp(2;2)dpp[d21], which together create a synthetic deletion for the Or22a and Or22b genes (commonly called “Delta halo” flies). Antennal olfactory receptor neuron ab3A loses its odorant response in flies lacking these genes. This “empty neuron” system (Dobritsa et al., 2003) allows the function of any odorant receptor to be tested in the absence of the naturally occurring odorant receptors.

Variants of Odorant receptor 4 from the mosquito, Aedes aegypti, expressed under UAS control. Mosquitoes differ in their preference for humans over other animals depending on the Or4 alleles they carry.

These stocks were described in McBride et al. (2014): Evolution of mosquito preference for humans linked to an odorant receptor, Nature 515: 222–227.

Odorant receptors from the mosquito, Anopheles gambiae, expressed under UAS control. The stocks were described in Carey et al. (2010): Odorant reception in the malaria mosquito Anopheles gambiae, Nature 464: 66–71.

Odorant receptors from the mosquito, Culex quinquefasciatus, expressed under UAS control.

Odorant receptors from the silk moth, Bombyx mori, expressed under UAS control.


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