Spinocerebellar ataxia type 6 (SCA6) is an adult-onset progressive disorder characterized by loss of motor coordination and balance accompanied by other neurodegenerative problems including speech difficulties, involuntary eye movements (nystagmus), and double vision. SCA6 is one of several diseases caused by an increase in the number of CAG repeats within the coding region of the disease gene (in this case the CACNA1A gene). Fly stocks in the Bloomington collection that can be used to study SCA6 are listed here.
General Information links for Spinocerebellar ataxia type 6:
- OMIM
- NCBI's GeneReviews
- National Library of Medicine's Genetic Home Reference