Myotonic dystrophies

Myotonic dystophy type 1 and type 2 are forms of muscular dystrophies caused by expansions of tri- and tetra-nucleotide repeats in non-coding RNA. In type 1, the repeat expansion is found in the 3' UTR of the dystrophia myotonica protein kinase gene (DMPK).  In type 2, the expansion is found in an intron of the zinc finger protein-9 gene (ZNF9).

See also our page on Muscular dystrophies.

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