Galactosemia is caused by an inability to metabolize galactose. It usually manifests during early infancy and can be life-threatening if not treated immediately. Long-term complications include cataracts, speech problems, developmental delays,intellectual disabilities and reproductive (ovarian) issues. Fly stocks in the Bloomington collection that can be used to study Galactosemia are listed here.

General information links for Galactosemia:

Galactosemia subtypes (from OMIM)
subtypeHuman gene symbolHuman gene full nameFly gene
Galactosemia, Type 1 (classic)GALTGalactose-1-phosphate uridylyltransferaseGalt
Galactokinase deficiency (Galactosemia, Type II)GALK1GalactokinaseGalk
Galactose epimerase deficiency (Galactosemia, Type III)GALEUDP-galactose-4-prime-epimeraseGale