Alzheimer disease

Genes for studying Alzheimer disease
Human gene(s)Human full nameFly geneOMIM link and/or comments
APH1A and APH1BAnterior pharynx defective 1A and 1Banterior pharynx defective 1 (aph-1)gamma-secretase complex member
APPAmyloid beta A4 Precursor Proteinbeta amyloid protein precursor-like (Appl)Alzheimer disease 1/precursor of peptide found in senile plaques
APLP1 and APLP2Amyloid beta A4 Precursor-like Protein 1 and 2  
BACE1beta-site Amyloid beta A4 Precursor Protein-cleaving enzyme 1 beta-secretase
Fe65/APBB1Amyloid beta A4 Precursor Protein-binding, family B, member 1 APP-binding protein
HSD17B10/ERABhydroxysteroid (17-beta) dehydrogenase 10scully (scu)multifunctional mitochondrial enzyme
MARK3, MARK1, MARK2, MARK4Microtubule affinity-regulating kinasepar-1tau kinase
NCSTNNicastrinNicastrin (Nct)gamma-secretase complex member
PSEN1 and PSEN2Presenilin-1 and Presenilin-2Presenilin (Psn)Alzheimer disease 3 and 4/gamma-secretase complex member
PEN2/PSENENPresenilin enhancer 2presenilin enhancer (pen-2)gamma-secretase complex member
Tau (MAPT)Microtubule-associated protein tautauneurofibrillary tangle component