Spinocerebellar Ataxia 2 (SCA2) is a progressive disorder associated with loss of motor coordination, impaired eye movement and mild dementia. SCA2 is one of several diseases caused by an increase in the number of CAG repeats within the coding region of the disease gene (in this case the ataxin 2/ATXN2 gene) and subsequent translation of those repeats into an expanded polyglutamine (polyQ) tract in the protein. Fly stocks in the Bloomington collection that can be used to study SCA2 are listed here.
General information links for SCA2:
General information links for ataxin 2: