Fragile X syndrome is the most common form of inherited intellectual disability. Disease severity can vary but all forms seem to be caused by expansion of a CGG repeat in the 5' untranslated region of the FMR1 gene that silences the gene. Fly stocks in the Bloomington collection that can be used to study Fragile X Syndrome are listed here.
General information links for Fragile X syndrome:
- NIH's Genetics Home Reference - includes links for GHR pages on FMR1
- NLM/NIH's Genetic and Rare Disease Information Center