Transpositions in Bloomington stocks

A transposition is generated by three chromosomal breakpoints and the movement of a chromosomal segment to a new position. A transposition can be separated into deletion and duplication components.

Transposition

Transpositions can be interchromosomal as shown in the figure, or they can be intrachromosomal so that the deletion and duplication components remain linked.

In general, transposition stocks in the Bloomington collection are maintained because the deletion and/or duplication chromosomes are useful for experiments, or because one of the breakpoints disrupts a gene.

  • Transpositions useful for their deletion and/or duplication components

    The following stocks have deletion and/or duplication components that can be useful in gene mapping, complementation and mutation rescue experiments. These stocks are used more frequently for their duplication components; consequently, they are also listed among cytologically defined duplication stocks.

  • Transpositions that cause mutations

    The following stocks are maintained because at least one transposition breakpoint disrupts a gene.

  • Incidental transposition

    We have one stock where the transposition is somewhat irrelevant. The stock is maintained for Df(2R)pk78k. The intrachromosomal transposition Tp(2;2)CA30 is present and the deletion and duplication components could potentially be separated and used in experiments, but, basically, it is incidental.