Transpositions in Bloomington stocks

A transposition is generated by three chromosomal breakpoints and the movement of a chromosomal segment to a new position. A transposition can be separated into deletion and duplication components.


Transpositions can be interchromosomal as shown in the figure, or they can be intrachromosomal so that the deletion and duplication components remain linked.

In general, transposition stocks in the Bloomington collection are maintained because the deletion and/or duplication chromosomes are useful for experiments, or because one of the breakpoints disrupts a gene.